Cyclic somatostatin( SRIF-14,Somatostatin-14 )

Catalog No. M22284 CAS No. 38916-34-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Cyclic somatostatin
Note

Research use only, not for human use.
Brief Description

Cyclic somatostatin is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.
Description

Cyclic somatostatin is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.
In Vitro

Cyclic somatostatin (0-10 μM; 15 min) dose-dependently inhibits the contractile response to isoprenaline in rat ventricular cardiomyocytes with an IC50 value of 13 nM.
In Vivo

Cyclic somatostatin (5 μg/kg; i.v. per hour once for 18-22 hours) affects visceral metabolism in ruminants. Animal Model:Polypay sheeps Dosage:5 μg/kg Administration:Intravenous injection; 5 μg/kg per hour once; for 18-22 hours Result:Decreased net portal-drained viscera release of glucose, a-amino N, ammonia N, b-hydrox ybutyrate, oxygen consumption, liver oxygen consumption, and total splanchnic a-amino N release and oxygen consumption. Increased lactate release and net hepatic glucose output.
Synonyms

SRIF-14,Somatostatin-14
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

CAS Number

38916-34-6
Formula Weight

1637.88
Molecular Formula

C76H104N18O19S2
Purity

>98% (HPLC)
Solubility

DMF:100 mg/mL (61.05 mM; Need ultrasonic);H2O:71.3 mg/mL (43.53 mM; Need ultrasonic and warming)
SMILES

C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O
Chemical Name

——

Calculator

molnova catalog